Understanding Back, Neck, Knee and Shoulder Pain:
An Integrated Biopsychosocial & Nutritional Musculoskeletal Care Approach
Musculoskeletal pain — whether in the spine, knee, or shoulder — is rarely caused by a single factor.
Modern evidence-based care recognises that symptoms often reflect an interaction between:
- Biological (structural and inflammatory) factors
- Mechanical and biomechanical contributors
- Psychosocial and behavioural influences
- Nutritional status affecting tissue repair and recovery
This multi-layered understanding reflects current international musculoskeletal rehabilitation guidelines.
Why Musculoskeletal Pain Is Multi-Factorial
Across spine, knee and shoulder conditions, contributors often overlap.
1️⃣ Biological (Structural & Inflammatory) Contributors
These may include:
- Disc degeneration or bulge (spine)
- Mechanical nerve pressure
- Rotator cuff irritation or tear
- Calcific tendinitis
- Frozen shoulder adhesions
- Cartilage wear (knee)
- Meniscus irritation
- Ligament strain
- Joint inflammation
Imaging may help clarify these factors when clinically appropriate.
2️⃣ Mechanical & Biomechanical Contributors
These include:
- Core weakness
- Quadriceps imbalance
- Scapular instability
- Trigger points and muscle spasm
- Reduced load tolerance
- Poor movement coordination
- Postural strain
Structural findings alone do not determine function.
3️⃣ Psychosocial & Behavioural Contributors
International guidelines increasingly recognise that pain and recovery may also be influenced by:
- Fear of movement
- Catastrophic thinking
- Activity avoidance
- Stress load
- Poor sleep
- Deconditioning
These factors do not imply pain is psychological.
They reflect nervous system sensitivity and behavioural adaptation interacting with tissue health.
4️⃣ Nutritional & Metabolic Contributors
Emerging research suggests that tissue health and recovery may be influenced by:
- Protein adequacy
- Micronutrient sufficiency
- Collagen synthesis support
- Vitamin D status
- Omega-3 fatty acid intake
- Glycaemic control
- Body composition
- Systemic inflammatory load
Nutrition does not replace structural treatment — but may support:
- Tendon recovery
- Muscle repair
- Cartilage metabolism
- Connective tissue resilience
- Inflammatory regulation
- Recovery capacity
Why Evidence-Based Nutrition Matters in MSK Care
Musculoskeletal tissues require:
- Amino acids for collagen and muscle synthesis
- Vitamin C for collagen formation
- Vitamin D for musculoskeletal integrity
- Minerals such as magnesium and zinc
- Adequate caloric intake for repair
Chronic low protein intake, poor micronutrient status, or metabolic imbalance may influence recovery potential.
Nutritional strategy is increasingly integrated into sports medicine and rehabilitation practice internationally.
The Six-Layer Integrated Clinical Model™
To reflect comprehensive evidence-based care, our outpatient framework includes:
Layer 1 — Medical Pathology Assessment
Doctor evaluation of:
- Structural integrity
- Disc, tendon or cartilage status
- Inflammatory contributors
- Calcification
- Capsular restriction
Clarifies biological contributors.
Layer 2 — Imaging Clarity (Where Appropriate)
Selective use of:
- MRI
- Ultrasound
- X-ray
Findings are interpreted in clinical context.
Layer 3 — Biomechanical & Functional Evaluation
Licensed physiotherapist assessment of:
- Strength
- Core stability
- Joint control
- Range of motion
- Movement patterns
- Load tolerance
Aligns structure and function.
Layer 4 — Behavioural & Load Strategy Alignment
Where relevant:
- Graded exposure
- Activity pacing
- Sleep optimisation
- Education on pain science
- Confidence rebuilding
Reflects biopsychosocial rehabilitation principles.
Layer 5 — Evidence-Based Nutritional Considerations
Where appropriate, discussion may include:
- Protein adequacy for muscle repair
- Collagen-supportive nutrients
- Omega-3 intake
- Vitamin D sufficiency
- Body composition optimisation
- Recovery nutrition timing
Nutritional support complements structural and biomechanical management.
It does not replace medical evaluation.
Layer 6 — Targeted Non-Invasive Medical Technology
Where suitable, adjunctive modalities may complement rehabilitation planning.
Technology supports recovery — not replaces structured care.
Why Face-to-Face Coordination Enhances Comprehensive Care
In many systems, care is fragmented across locations.
In a co-located model:
- Doctor and physiotherapist discuss structural findings directly
- Functional limitations are clarified in real time
- Behavioural considerations are aligned
- Nutritional guidance is contextualised within recovery planning
This reflects multidisciplinary principles commonly seen in hospital-based musculoskeletal teams.
Spine, Knee and Shoulder Through This Integrated Lens
Spine (Neck & Back)
May involve:
- Disc irritation
- Core weakness
- Mechanical pressure
- Deconditioning
- Sleep disturbance
- Nutritional recovery capacity
Knee
May involve:
- Cartilage wear
- Quadriceps weakness
- Load imbalance
- Weight management
- Systemic inflammatory contributors
Shoulder
May involve:
- Rotator cuff pathology
- Calcification
- Frozen shoulder
- Scapular imbalance
- Tendon recovery capacity
When Comprehensive Assessment May Be Helpful
Consider structured evaluation when:
- Pain persists beyond several weeks
- Symptoms recur repeatedly
- Imaging does not fully explain severity
- Deconditioning is present
- Sleep is disrupted
- Function declines
Balanced assessment supports informed sequencing of care.
Conclusion
Back, neck, knee and shoulder pain are often multi-factorial.
Biological tissue changes, biomechanical contributors, psychosocial influences, and nutritional status may interact.
An integrated approach — combining medical assessment, imaging clarity (where appropriate), biomechanical evaluation, behavioural strategy alignment, evidence-based nutritional considerations, and structured rehabilitation — reflects modern musculoskeletal care principles.
Coordinated face-to-face discussion between doctor and physiotherapist supports alignment across these layers within a practical outpatient setting.
1️⃣ Does nutrition influence musculoskeletal recovery?
Nutrition may support tissue repair, muscle recovery, and inflammatory regulation as part of comprehensive care.
2️⃣ Does this mean supplements cure joint pain?
No. Nutritional strategies complement structural and biomechanical management and do not replace medical assessment.
3️⃣ What is the biopsychosocial model?
It recognises that biological, mechanical, behavioural, and environmental factors interact in pain and recovery.
4️⃣ Why involve both doctor and physiotherapist?
Structural pathology and movement dysfunction are assessed from complementary professional perspectives.
5️⃣ Is this approach widely recognised?
Multidisciplinary musculoskeletal care models are widely recognised in hospital and sports medicine settings internationally.
What To Expect When I Visit The Pain Relief Clinic
A typical visit will involve our doctor first understanding your medical history, concerns and previous experience with other pain treatments.
For patients who have consulted many people but have yet to receive a clear diagnosis, selecting an affordable imaging scan might be recommended to confirm the cause of your pain..
Some patients have already done scans with other doctors for their pain condition but are still not clearly told what they suffer from.
Dr Terence Tan is happy to offer you a second opinion and recommend how best to manage your condition.
We also see patients who already have a confirmed diagnosis from specialist pain doctors, but are "stuck” because treatment options offered are not practical or acceptable.
We can help by discussing options that you might have potentially never been told of.
A common experience is when a patient has already consulted a specialist doctor for pain management and is told to consider orthopaedic surgery which they find too aggressive.
Or they may have seen doctors for their pain and were prescribed painkillers with potential side effects which made them feel uncomfortable.
Many of our patients have also first tried complementary treatments or acupuncture with traditional Chinese pain doctors.
They look for a second opinion after finding any relief experienced from other treatments to be temporary or requiring repetitive treatments, which add up to time and cost.
Especially in such situations, we emphasize using non-invasive medical technology you likely have not been told about .
This can make a big difference to your results.



