Some of the possible signs and symptoms of Rheumatoid arthritis include:

• Low-grade fever

• Fatigue and tiredness

• Lack of appetite

• Small joints in the fingers, toes, hands, feet, wrists, elbows, and ankles becoming swollen and painful

• Large joints like knee joint, can also be affected

• Pain and swelling is symmetric (same joint on both sides)

• Joints later become stiff and deformity may also occur

• Morning stiffness of affected joints which occurs after waking up in the morning and lasts for at least 30 minutes.

• Stiffness after prolonged inactivity of affected joints

• Subcutaneous nodules which are hard swellings just under the skin may be present.